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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 1
1966 1
1970 1
1975 7
1976 10
1977 6
1978 11
1979 13
1980 9
1981 13
1982 14
1983 36
1984 36
1985 43
1986 29
1987 40
1988 39
1989 41
1990 36
1991 31
1992 38
1993 53
1994 54
1995 53
1996 36
1997 34
1998 44
1999 46
2000 42
2001 44
2002 40
2003 38
2004 43
2005 37
2006 36
2007 45
2008 53
2009 42
2010 37
2011 59
2012 75
2013 78
2014 78
2015 71
2016 80
2017 74
2018 55
2019 53
2020 44
2021 52
2022 44
2023 54
2024 20

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1,954 results

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Page 1
Polyamine metabolism controls B-to-Z DNA transition to orchestrate DNA sensor cGAS activity.
Zhao C, Ma Y, Zhang M, Gao X, Liang W, Qin Y, Fu Y, Jia M, Song H, Gao C, Zhao W. Zhao C, et al. Immunity. 2023 Nov 14;56(11):2508-2522.e6. doi: 10.1016/j.immuni.2023.09.012. Epub 2023 Oct 16. Immunity. 2023. PMID: 37848037
Cyclic guanosine monophosphate (GMP)-AMP (cGAMP) synthase (cGAS) is a universal double-stranded DNA (dsDNA) sensor that recognizes foreign and self-DNA in the cytoplasm and initiates innate immune responses and has been implicated in various infectious and non-infec …
Cyclic guanosine monophosphate (GMP)-AMP (cGAMP) synthase (cGAS) is a universal double-stranded DNA (dsDNA) sensor that recognizes fo …
Non-B-Form DNA Is Enriched at Centromeres.
Kasinathan S, Henikoff S. Kasinathan S, et al. Mol Biol Evol. 2018 Apr 1;35(4):949-962. doi: 10.1093/molbev/msy010. Mol Biol Evol. 2018. PMID: 29365169 Free PMC article.
We also detected dyad symmetries and predicted non-B-form DNA structures at neocentromeres, which form at ectopic loci. We propose that centromeres form at non-B-form DNA because of dyad symmetries or are strengthened by sequence-specific …
We also detected dyad symmetries and predicted non-B-form DNA structures at neocentromeres, which form at ectopic loci. …
Non-B-form DNA tends to form in centromeric regions and has undergone changes in polyploid oat subgenomes.
Liu Q, Yi C, Zhang Z, Su H, Liu C, Huang Y, Li W, Hu X, Liu C, Birchler JA, Liu Y, Han F. Liu Q, et al. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2211683120. doi: 10.1073/pnas.2211683120. Epub 2022 Dec 27. Proc Natl Acad Sci U S A. 2023. PMID: 36574697 Free PMC article.
Thus far, systematic studies into the organization and function of non-B-form DNA in plants remain scarce. Here, we applied the oat system to investigate the role of non-B-form DNA in centromeres. ...Taken together, our study elucidates t …
Thus far, systematic studies into the organization and function of non-B-form DNA in plants remain scarce. Here, we app …
Targeting non-B-form DNA in living cells.
Du Y, Zhou X. Du Y, et al. Chem Rec. 2013 Aug;13(4):371-84. doi: 10.1002/tcr.201300005. Epub 2013 Jul 4. Chem Rec. 2013. PMID: 23828823 Review.
Under certain conditions, repetitive DNA motifs have the potential to adopt non-B-form DNA structures, such as hairpins, triplexes, Z-DNA, quadruplexes, and i-motifs. ...In this review, we describe the latest studies on molecules that target non …
Under certain conditions, repetitive DNA motifs have the potential to adopt non-B-form DNA structures, such as h …
Crystal structures of 'ALternative Isoinformational ENgineered' DNA in B-form.
Shukla MS, Hoshika S, Benner SA, Georgiadis MM. Shukla MS, et al. Philos Trans R Soc Lond B Biol Sci. 2023 Feb 27;378(1871):20220028. doi: 10.1098/rstb.2022.0028. Epub 2023 Jan 11. Philos Trans R Soc Lond B Biol Sci. 2023. PMID: 36633282 Free PMC article.
Thus, artificial DNA seeking to mimic the properties of natural DNA should also be able to adopt B-form. ...This finding suggests that ALIEN DNA may have a larger repertoire of B-form structures than natural DNA. ...
Thus, artificial DNA seeking to mimic the properties of natural DNA should also be able to adopt B-form. ...This …
Dehydrated DNA in B-form: ionic liquids in rescue.
Ghoshdastidar D, Senapati S. Ghoshdastidar D, et al. Nucleic Acids Res. 2018 May 18;46(9):4344-4353. doi: 10.1093/nar/gky253. Nucleic Acids Res. 2018. PMID: 29669113 Free PMC article.
Here, we show that ionic liquids, an emerging class of green solvents, can induce conformational transitions in DNA and even rescue the dehydrated DNA in the functional B-form. CD spectroscopic analyses not only reveal rapid transition of A-DNA
Here, we show that ionic liquids, an emerging class of green solvents, can induce conformational transitions in DNA and even rescue t …
G-Quadruplex DNA and Other Non-Canonical B-Form DNA Motifs Influence Productive and Latent HIV-1 Integration and Reactivation Potential.
Ajoge HO, Kohio HP, Paparisto E, Coleman MD, Wong K, Tom SK, Bain KL, Berry CC, Arts EJ, Barr SD. Ajoge HO, et al. Viruses. 2022 Nov 11;14(11):2494. doi: 10.3390/v14112494. Viruses. 2022. PMID: 36423103 Free PMC article.
To better understand the local genomic environment surrounding HIV-1 proviruses, we assessed the influence of non-canonical B-form DNA (non-B DNA) on the HIV-1 integration site selection. We showed that productively and latently infected cells exhibit …
To better understand the local genomic environment surrounding HIV-1 proviruses, we assessed the influence of non-canonical B-form
Non-B-form DNA is associated with centromere stability in newly-formed polyploid wheat.
Yi C, Liu Q, Huang Y, Liu C, Guo X, Fan C, Zhang K, Liu Y, Han F. Yi C, et al. Sci China Life Sci. 2024 Apr 16. doi: 10.1007/s11427-023-2513-9. Online ahead of print. Sci China Life Sci. 2024. PMID: 38639838
However, the role of non-B-form DNA in centromeres, especially in polyploid wheat, remains elusive. ...We found that three of these non-B-form DNA motifs were enriched at centromeric regions, especially at the CENH3-binding sites, suggest …
However, the role of non-B-form DNA in centromeres, especially in polyploid wheat, remains elusive. ...We found that th …
Sequence-dependent cost for Z-form shapes the torsion-driven B-Z transition via close interplay of Z-DNA and DNA bubble.
Kim SH, Jung HJ, Lee IB, Lee NK, Hong SC. Kim SH, et al. Nucleic Acids Res. 2021 Apr 19;49(7):3651-3660. doi: 10.1093/nar/gkab153. Nucleic Acids Res. 2021. PMID: 33744929 Free PMC article.
Despite recent genome-wide investigations of functional DNA elements, the mechanistic details about their actions remain elusive. One intriguing possibility is that DNA sequences with special patterns play biological roles, adopting non-B-DNA conformations. . …
Despite recent genome-wide investigations of functional DNA elements, the mechanistic details about their actions remain elusive. One …
Thermal Conductivity of B-DNA.
Mahalingam V, Harursampath D. Mahalingam V, et al. J Phys Chem B. 2021 Feb 11;125(5):1363-1368. doi: 10.1021/acs.jpcb.0c09288. Epub 2021 Feb 1. J Phys Chem B. 2021. PMID: 33523668
The thermal conductivity of B-form double-stranded DNA (dsDNA) of the Drew-Dickerson sequence d(CGCGAATTCGCG) is computed using classical molecular dynamics (MD) simulations. In contrast to previous studies, which focus on a simplified 1D model or a coarse-gr …
The thermal conductivity of B-form double-stranded DNA (dsDNA) of the Drew-Dickerson sequence d(CGCGAATTCGCG) is comput …
1,954 results